"B" All Calm Free Sample

"B" All Calm Free Sample

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Herbs and Supplements:

Several supplements promote stress and anxiety reduction. Here is a brief overview of some of the most common ones:

  • St John's Wort:
    • St. John’s Wort (Hypericum perforatum), a plant that grows in the wild, has been used for centuries for mental health conditions. It’s widely prescribed for depression in Europe.
    • According to the National Institute of Health "A 2008 review of 29 international studies suggested that St. John’s wort may be better than a placebo and as effective as different standard prescription antidepressants for major depression of mild to moderate severity. St. John’s wort also appeared to have fewer side effects than standard antidepressants."
      The possible mechanism that causes St John's Wort to be an effective as a natural antidepressant is a rare combination of antidepressant chemicals that prevent or delay the re-uptake of the hormones serotonin, dopamine and norepinephrine, thereby reducing depressive symptoms.
      • They are hypericin and pseudohypericin. Both active compounds in St. John's wort that have been shown to fight depression and viral syndromes.
    • A 2017 analysis of 27 studies determined that St. John’s wort had similar effects on mild to moderate depression as antidepressants. Those researchers also noted that fewer people stopped taking St. John’s wort, compared to antidepressants. (NIH Review Link)
    • According to an article posted by Healthline E-magizine; Jeremy Wolf, a licensed naturopathic physician, explained that St. John’s wort creates many actions in the body.
      • “It is a strong antidepressant and may elevate mood in individuals with mild to moderate depression,” he said.
        He notes that St. John’s wort is not recommended for individuals with severe depression.
      • Wolf said St. John’s wort also has strong antiviral activity that may also promote healing and repair of wounds.
      • He cautioned that the herb is not a fast-acting cure. It may take weeks or months before you notice any effect.
    • Studies have shown that the Hypericum plant, also known as St. John's wort, has mild antidepressant effects. Standardized formulations are supposed to contain 0.3% hypericin, the plant extract. However, few published studies have examined commercially available products for the amounts of hypericin and pseudohypericin -- both active compounds in St. John's wort that have been shown to fight depression and viral syndromes.
    • St. John's Wort has a long history of use in relation to anxiety and nervous tension. It has been studied and used as a mood leveler for over 2,000 years.
    • It currently being prescribed in Europe as an effective mood-leveling supplement.
      • "A 2009 systematic review of 29 international studies suggested that St. John’s wort may be better than a placebo (an inactive substance that appears identical to the study substance) and as effective as standard prescription antidepressants for major depression of mild to moderate severity. St. John’s wort also appeared to have fewer side effects than standard antidepressants." (Citation)
  • Valerian Root:
    • This herb has a long history of being used for many health conditions.
    • Valerian Root has a history of being used as a sleep aid, for anxiety relief. Greek physicians Dioscorides and Galen touted it as a remedy for poison. It was used as a cure for epilepsy in the Middle Ages.
    • The most common historical use for Valerian is as a treatment for nervous disorders. There are current studies that are testing the efficacy of Valerian Root for different nervous system issues.
    • In the 16th century Valerian was used to treat nervousness, trembling and headaches.
    • Most studies seem to indcate that Valerian has two active componants that contribute to its effectiveness.
      • First is valerenic acid and its derivatives, which have demonstrated sedative properties in animal studies (Hendriks H, Bos R, Allersma DP, Malingre M, Koster AS: Pharmacological screening of valerenal and some other components of essential oil of Valeriana officinalis. Planta Medica 42: 62-68, 1981)
      • And second are the iridoids, which include the valepotriates. Valepotriates and their derivatives are active as sedatives in vivo.
        • Both of these seem to act as a sedative individually however there are other componants in Valerian that also have effects on the nervous system without the inclusion of valerenic acid or valerian iridoids. It may be possible that there are more nervous system active componants still left to study.
      • A possible mechanism by which a valerian extract may cause sedation is by increasing the amount of gamma aminobutyric acid (GABA, an inhibitory neurotransmitter) available in the synaptic cleft. Studies are still needed to prove or disprove this theory.
  • B Vitamins:
    • B Vitamins have been used traditionally as mood leveling supplements. Here at Grandma's Herbs we call them the happy vitamins.
      • A statement issued in a study found on pubmed.gov is "After individual differences in personality and work demands were statistically controlled, the vitamin B complex treatment groups reported significantly lower personal strain and a reduction in confusion and depressed/dejected mood after 12 weeks."
    • In a study titled "Reducing occupational stress with a B-vitamin focussed intervention: a randomized clinical trial:" it was concluded that:
      • "Occupational stress is a multibillion dollar problem. Effective strategies reducing occupational stress are urgently required. Dietary supplementation with B group vitamins may be an economically viable and sustainable intervention. Reducing occupational stress will have enormous benefits for decreasing stress claims, absenteeism, and increasing work productivity. Vitamin B supplementation is also likely to have additional health and quality of life benefits."
  • Magnesium:
    • Magnesium is a mineral that plays a role in over 300 enzymatic reactions within the body, including the metabolism of food, synthesis of fatty acids and proteins, and the transmission of nerve impulses.
    • Findings in current studies offer modest support that Magnesium (Mg) intake confers benefits for individuals with pre-existing mild to moderate levels of anxiety. This comes from an analysis of 8 different studies of Magnesium and mild stress/anxiety.(PMC Article Link)
    • Reductions in magnesium levels, or changes in the way that it is processed, have been linked to increased levels of anxiety.
      • This appears to related activity in the hypothalamic-pituitary-adrenal (HPA) axis, a set of three glands that control a person's reaction to stress.
      • Research has shown that a low-magnesium diet may alter the types of bacteria present in the gut, and this may impact anxiety-based behavior. (National Institute of Health Study Publication)
  • GABA (Gamma Aminobutyric Acid):
    • Gamma-aminobutyric acid is a neurotransmitter that helps send messages between the brain and the nervous system. It is produced in the brain from glutamate. This process is catalyzed by the active form of vitamin B6 and the enzyme glutamate decarboxylase.
    • GABA currently being studied for the effects it has in relation to stress and anxiety.
      • "In conclusion, GABA could work effectively as a natural relaxant and its effects could be seen within 1 hour of its administration to induce relaxation and diminish anxiety." (PubMed.gov Article Link)
    • The significance of this key neurotransmitter has just recently been recognized, but it is now thought that it plays a role in a multitude of health conditions, including ADHD, insomnia, depression and anxiety.
    • The mechanism of action is believed to reduce feelings of of anxiety and fear by decreasing neuronal excitability.
  • 5-Hydroxytryptophan (5-HTP):
    • 5-HTP is an amino acid. It is essential for the manufacturing of serotonin in the brain.
      • Serotonin is an important chemical and neurotransmitter in the human body. It is believed to help regulate mood and social behavior.
    • Research done on 5-HTP showed that in a double-blind study, 58 percent of generally anxious patients reported significantly greater reduction in baseline anxiety compared to individuals who received a placebo.
  • Supplementing with 5-HTP can help to treat a number of issues that are associated with anxiety, including trouble sleeping, moodiness and headaches.

The studies sited above are for informational purposes only. They do not reflect or relate to the performance or purpose of any products that contain similar materials.

Health Information

Is Your Life Plagued With Stress?

Many people today suffer from stress, anxiety, nervousness and tension from today's modern lifestyle. The workplace, the home, the 24 hour news cycle and its constant barrage of stressful world events all contribute to feeling overwhelmed and weighed down.

What is stress?

We feel that stress is the umbrella word that best defines what we feel when we are anxious, nervous or tense.

In psychology, stress is a feeling of strain and pressure. Stress is a type of psychological pain. Small amounts of stress may be desired, beneficial, and even healthy. Positive stress helps improve athletic performance. It also plays a factor in motivation, adaptation, and reaction to the environment. On the other hand stress can affect people of all ages, genders and circumstances and can lead to both physical and psychological health issues.

Stressors can be external (from the environment, psychological, or social situations) or internal (illness, or from a medical procedure). Stress can initiate the "fight or flight" response, a complex reaction of neurologic and endocrinologic systems or it can be debilitating in the case of chronic stress.

The point is that we all live with some stress and pressure. Sometimes it can lead to immediate reactions to adverse events that help our situation. More often than not the constant pressure that causes us to be "stressed out" may cause temporary bouts of depression and may even debilitate us enough that we become "stress paralized" (a state where one is unable to react to the situation at hand).

Stress: a state of mental or emotional strain or tension resulting from adverse or very demanding circumstances. The very definition of stress might cause some consternation.

How to deal with stress. There are several different ways that one can deal with stress. Here is a list of just a few.

  • Exercise:
    • Exercise is one of the most important things you can do to combat stress.
      It might seem contradictory, but putting physical stress on your body through exercise can relieve mental stress. The benefits are strongest when you exercise regularly. People who exercise regularly are less likely to experience anxiety than those who don't exercise.
    • There are a few reasons behind this:
    • Stress hormones: Exercise lowers your body's stress hormones — such as cortisol — in the long run. It also helps release endorphins, which are chemicals that improve your mood and act as natural painkillers.
    • Sleep: Exercise can also improve your sleep quality, which can be negatively affected by stress and anxiety.
    • Confidence: When you exercise regularly, you may feel more competent and confident in your body, which in turn promotes mental wellbeing.
  • Reduce Caffeine Intake:
    • Caffeine is a stimulant found in coffee, tea, chocolate and energy drinks. High doses can increase anxiety. People have different tolerences of caffeine. Since caffeine is a metabolism booster it might add to a stressful situation. If you feel overly anxious at home or at work it might be a good idea to keep the caffeine intake to a minimum.
  • Laugh!!!
    • Laughter truly is the best medicine.
    • It's hard to feel anxious when you're laughing. It's good for your health, and there are a few ways it may help relieve stress:
      • Relieving your stress response.
      • Relieving tension by relaxing your muscles.
      • In the long term, laughter can also help improve your immune system and mood.
      • Try watching a funny TV show or hanging out with friends who make you laugh.
  • Yoga:
    • YES those odd poses that seem to contort bodies in ways that they just shouldn't bend are good for you physically and emotionally!
    • Yoga has become a popular method of stress relief and exercise among all age groups.
      • While yoga styles differ, most share a common goal — to join your body and mind.
      • Yoga primarily does this by increasing body and breath awareness.
        • Some studies have examined yoga's effect on mental health.
        • Overall, research has found that yoga can enhance mood and may even be as effective as antidepressant drugs at treating depression and anxiety.
    • In general, the benefit of yoga for stress and anxiety seems to be related to its effect on your nervous system and stress response.
    • It may help lower cortisol levels, blood pressure and heart rate and increase gamma-aminobutyric acid (GABA), a neurotransmitter that is lowered in mood disorders.
  • Meditate while listening to soothing music.
    • Meditation has been around just about as long as civilization. We know that meditation allows us to become calm and collected.
    • Adding slow soothing music to meditation can multiply the effects of the meditation itself.
      • The music should be instrumantal nad should be calming in YOUR opinion. We all have different tastes in music and therefore what you choose as calming should work.


  • Vitamin B1 (as Thiamin), Vitamin B2 (as Riboflavin), Vitamin B3 (as Niacinamide), Vitamin B6 (as Pyridoxine HCL), Folic Acid, Vitamin B12 (as Cobalamin 1%), Biotin (1%), Vitamin B5 (as Pantothenic Acid), Magnesium (as A.A. Chelate), Zinc (as Acetate), Chromium (as Polyniconate 10%)
  • Herbs: St. John Wort (whole), Ginkgo Biloba (leaf), GABA Inositol (USP), Choline (as Bitartate), Valerian (root), Passion Flower (herb), Griffonia Extract 25% (5-HTP)


  • 2 Capsules each morning with food. Take an additional 4 to 6 per day as needed.

What's included

  • 1 bottle of Grandma's Herbs "B" ALL CALM
    • 100 Capsules


  • Promotes feelings of well-being.
  • Uses studied ingredients like B vitamins, GABA, Magnesium and St John's Wort.
  • Promotes feelings of health, well being and confidence.


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