Night Nervine herbal formula by Grandma's Herbs, showing a bottle of natural herbal supplement for sleep support.
Bottle of Grandma's Herbs Night Nervine natural herbal formula for calming nerves and promoting restful sleep.
Herbal formula Night Nervine by Grandma's Herbs showing natural ingredients in a jar for calming and sleep support.
Night Nervine herbal formula by Grandma's Herbs, showing a bottle of natural herbal supplement for restful sleep and relaxation.
Herbal product Night Nervine by Grandma's Herbs, showing natural herbal formula in a glass jar with dried herbs and a wooden spoon.
Night Nervine herbal formula by Grandma's Herbs, showing a bottle of natural herbal supplement for sleep support.
Bottle of Grandma's Herbs Night Nervine natural herbal formula for calming nerves and promoting restful sleep.
Herbal formula Night Nervine by Grandma's Herbs showing natural ingredients in a jar for calming and sleep support.
Night Nervine herbal formula by Grandma's Herbs, showing a bottle of natural herbal supplement for restful sleep and relaxation.
Herbal product Night Nervine by Grandma's Herbs, showing natural herbal formula in a glass jar with dried herbs and a wooden spoon.

Since 1979 · St. George, Utah

Night Nervine -Natural Herbal Formula

A nighttime herbal formula made to support relaxation and restful, quality sleep.*
$20.99 USD $23.44 Sale Save $2.45
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100 capsules per bottle
  • Supports the body's natural ability to relax and unwind at the end of the day
  • Helps promote restful, quality sleep as part of a healthy nighttime routine
  • Traditionally formulated with botanicals long valued for their calming, evening-time use
  • Encourages a sense of ease and tranquility before bed
  • 30-day returns
  • Ships in 1–3 days
  • GMP certified · USA
  • No fillers or additives
"I love the Night-nervine capsules! They help me to fall asleep faster and to sleep deeper than I have in years."Merrica C. · verified buyer
Night Nervine -Natural Herbal Formula$20.99
100% Pure

100% Pure

No fillers, additives, or artificial ingredients

Quality You Can Trust

Quality You Can Trust

Made in the USA in GMP certified facilities

Made with Care

Made with Care

Crafted with love and traditional wisdom

How to Take

01

Take 2–4 Capsules

Recommended bedtime serving.

02

One Hour Before Bed

Take before sleep.

03

Adjust If Needed

Increase intake when desired.

What's inside

Eleven ingredients. Nothing else.

No fillers, no additives, no artificial ingredients.

Hopsflower
Valerianroot
Blue Vervainherb
Skullcapherb
St John's Wortherb
Black Cohoshroot
Lady's Slipperroot
Lily of the Valleyherb
Bladder Podherb
Mistletoeherb
Spearmintleaf

The key botanicals

A closer look

Valerian Root

Valeriana officinalis

  • Historical Use: Valerian root has been used for centuries in traditional herbal practices, with references dating back to Greek physicians like Dioscorides and Galen.
  • Mood and Nervous System Support: Valerian is often associated with maintaining a calm and balanced mood. Its bioactive components, such as valerenic acid and iridoids (including valepotriates), are thought to interact with the body’s natural processes to support the nervous system.
  • Mechanism of Action: Research suggests that valerian may influence gamma-aminobutyric acid (GABA) activity, a neurotransmitter involved in regulating mood and nervous system responses.

Hops

Humulus lupulus

  • Rich in Bioactive Compounds: Hops contain natural compounds such as flavonoids, including xanthohumol and 8-prenylnaringenin, as well as essential oils like humulene and lupuline. These bioactive components are widely studied for their potential health-supporting properties.
  • Promotes Relaxation: Compounds found in hops are thought to support the body's natural relaxation processes. These properties have made hops a popular ingredient in herbal supplements aimed at promoting a sense of calm.
  • Supports Healthy Sleep: Hops have a long history of use in traditional wellness practices to promote healthy sleep patterns. They are often combined with other herbs like valerian to promote calming feelings.

Since 1979

Forty-five years of the same formulas

Grandma's Herbs began in 1979 in St. George, Utah, when Master Herbalist Joseph VanSeters started making natural remedies from time-honored herbal knowledge — six formulas, on a kitchen counter.

Four decades later they're still made the same way, in the same place, by the same family. The tagline has never changed either: “Because They Work.”

1979Est. St. George, UT
40+Herbal formulas
45Years of trust

“Because They Work.”

Every formula is made in the USA in GMP-certified facilities, with no fillers, additives, or artificial ingredients.

Read our story →

Before you buy

Common questions

When will I notice something?

Herbs work gradually — give it consistent daily use over a few weeks. Everyone is different, so we set an honest expectation rather than an exciting one.

How long does one bottle last?

100 capsules — see the label for the suggested serving.

Do I need to change my diet?

No special diet or fasting is required. Take with plenty of water, as directed on the label.

Can I take it with other Grandma's Herbs formulas?

Many customers combine formulas as part of a broader routine. If you take medication or have a medical condition, check with your healthcare provider first.

What's in it — any fillers?

No fillers, additives, or artificial ingredients. Made in the USA in GMP-certified facilities.

What if it isn't for me?

You have 30 days from delivery to request a return — just reach out.

Full details

Everything about this formula

Features
  • Night Nervine is formulated of herbs in the NERVINE category.
  • Natural Herbal Formula.
  • Night Nervine promotes a healthy nervous system function.
What's Included

1 Bottle of Grandma's Herbs NIGHT NERVINE 100 Capsules 

Ingredients

Hops (flower), Valerian (root), Blue Vervain (herb), Skullcap (herb), St John's Wort (herb), Black Cohosh (root), Lady's Slipper (root), Lily of the Valley (herb), Bladder Pod (herb), Mistletoe (herb), Spearmint (leaf)

Instructions

Take 2 capsules 1 hour before bedtime. You may use more if needed.

Health Information

Getting adequate sleep is essential for maintaining overall health and well-being. During sleep, the body carries out critical functions such as repairing tissues, supporting immune system function, and processing information gained throughout the day. Proper sleep also supports cognitive functions like memory consolidation and decision-making. Ensuring restful and sufficient sleep helps the body restore its energy levels and allows for the maintenance of healthy bodily systems, including the nervous and cardiovascular systems.

Research
  • Valerian Root: Supporting Nervous System Balance
    • Historical Use:
      Valerian root (Valeriana officinalis) has been used for centuries in traditional herbal practices, with references dating back to Greek physicians like Dioscorides and Galen. It has a long-standing reputation for supporting a healthy nervous system and promoting emotional balance.

    • Mood and Nervous System Support:
      Valerian is often associated with maintaining a calm and balanced mood. Its bioactive components, such as valerenic acid and iridoids (including valepotriates), are thought to interact with the body’s natural processes to support the nervous system.

    • Mechanism of Action:
      Research suggests that valerian may influence gamma-aminobutyric acid (GABA) activity, a neurotransmitter involved in regulating mood and nervous system responses. By supporting GABA availability in the central nervous system, valerian root is thought to help maintain a healthy equilibrium during times of restlessness. Additional studies are ongoing to further explore these mechanisms and their potential benefits.



  • St. John’s Wort: Supporting a Healthy Nervous System

    • Historical Significance:
      St. John’s Wort (Hypericum perforatum) is a flowering plant with a long history of use in traditional herbal practices. Widely utilized in Europe, it is often included in formulations aimed at promoting nervous system balance and maintaining a healthy mood.

    • Key Active Compounds:
      The primary active compounds in St. John’s Wort, hypericin and pseudohypericin, are thought to support the nervous system by influencing the body's natural processes related to neurotransmitter levels. These compounds may play a role in the regulation of serotonin, dopamine, and norepinephrine, which are associated with mood and emotional balance.

    • Additional Bioactive Components:
      Recent studies suggest that hyperforin and adhyperforin, additional compounds found in St. John’s Wort, may also contribute to its effects. These components are believed to interact with chemical messengers in the nervous system, supporting mood stability and maintaining a sense of balance during periods of emotional fluctuation. Further research is ongoing to better understand the mechanisms of these compounds.


Hops: Supporting Relaxation and Sleep

  • Rich in Bioactive Compounds
    Hops (Humulus lupulus) contain natural compounds such as flavonoids, including xanthohumol and 8-prenylnaringenin, as well as essential oils like humulene and lupuline. These bioactive components are widely studied for their potential health-supporting properties.

  • Promotes Relaxation
    Compounds found in hops are thought to support the body's natural relaxation processes. These properties have made hops a popular ingredient in herbal supplements aimed at promoting a sense of calm.

  • Supports Healthy Sleep
    Hops have a long history of use in traditional wellness practices to promote healthy sleep patterns. They are often combined with other herbs like valerian to promote calming feelings.

  • Traditional and Modern Use
    The relaxing properties of hops continue to be studied in both historical and modern contexts, making them a popular choice for those seeking to support their overall sense of calm and well-being.

Skullcap:

  • Skullcap: Supporting Nervous System Health

    • Traditional Use
      Skullcap (Scutellaria lateriflora) has a long history of traditional use, particularly for supporting a "zen" state of mind. Historical references describe it as a nervine herb valued for its potential to nourish and support the central nervous system.

    • Role as a Nervine
      Nervines are herbs traditionally associated with helping to balance and support of the nervous system function. Skullcap is often included in wellness formulations for its role in promoting a sense of calm.

    • Antioxidant Support
      Skullcap contains bioactive compounds with antioxidant properties. These compounds may help the body maintain balance by neutralizing free radicals, which can contribute to oxidative stress. Research suggests that reducing oxidative stress supports overall nervous system function and promotes a relaxed state of mind.

    • Ongoing Research
      While its traditional uses are well-documented, modern research continues to explore the potential benefits of skullcap, including its effects on oxidative stress and nervous system health. It remains a popular choice in herbal supplements aimed at promoting calm and balance.

The information provided above is for educational purposes only and does not pertain to the performance or intended use of any specific products featured on this website.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.